Grey's Anatomy will air its fifth episode of the season tonight, Oct. 22 and things will be awkward!

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In the episode that is called "Guess Who's Coming to Dinner?" Dr. Meredith Grey (Ellen Pompeo), Dr. Maggie Pierce (Kelly McCreary) and Dr. Amelia Shepherd (Caterina Scorsone) will host a dinner party, but things will not entirely go over well.

According to the press release, Maggie will actually end up bailing on her cooking duties since she'll be at Grey Sloan Memorial, but that doesn't mean dinner won't be served. Dr. April Kepner (Sarah Drew) will step in to help cook as an attempt to avoid her husband Dr. Jackson Avery (Jesse Williams) actually.

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Meanwhile, Dr. Arizona Robbins (Jessica Capshaw) will become anxious as she waits to find out more about Dr. Callie Torres' (Sara Ramirez) new girlfriend.

In the sneak peek clip below, Callie actually begins to introduce her new girlfriend Penny (Samantha Sloyan). Penny may actually look familiar since the same actress portrayed the doctor that attempted to save Dr. Derek "McDreamy" Shepherd's (Patrick Dempsey) life, but failed. Plus, all those flashbacks to Derek's death occurred at the end of the last episode when Meredith answered the door.

As Amelia makes small talk with Penny and Callie, Meredith watches from the kitchen and seems zoned out as her eyes are focused on Penny and only Penny. Penny even seems to keep glancing at Meredith.

Dr. Alex Karev (Justin Chambers) will join Meredith in the kitchen and pick up on her off behavior so he'll ask her, "What's going on? Are you alright?"

Meredith will shrug it off as she continues going about her kitchen duties.

"Yes, I'm great. How are you?" Meredith will state, but Alex isn't buying it.

"You're not great. You're freaked out and you're smiling a lot," Alex counters.

Meredith chalks up her behavior to the dinner party, which earns another comment from Alex.

"[It's] like you're in a hostage video or something! Something's wrong!" Alex dishes.

Grey's Anatomy airs on ABC on Thursdays at 8 p.m. ET.

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Greys anatomy, Television, ABC