The Tonight Show has a new host, and Jimmy Fallon will be making his debut when the clock strikes midnight.

Jimmy Fallon Premieres The 'Tonight Show'; Find Out Spoilers & Guests, What To Expect From Jay Leno's Replacement

Taking Jay Leno's place on the NBC late night show, Fallon will premiere his new act from the opposite side of the country. Now airing from New York City and newly minted as The Tonight Show Staring Jimmy Fallon, the series will be getting a breath of fresh air as Fallon's inaugural week gets underway.

The 39-year-old comedian has refined his work over the last year and is looking forward to merging his loyal Late Night fanbase with Leno's constituency.

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"The show I'm doing now is the Tonight Show. We're not changing anything; the show will grow as I grow. We're just going to keep the best bits," Fallon informed USA Today, claiming that he has removed "a lot of the dumber stuff that didn't work, that's a little sophomoric, will be gone. But we've kind of gotten rid of that over the last year."

Fallon's first guests will include Will Smith and U2 on Monday while Jerry Seinfeld, Kristen Wiig, Bradley Cooper, Will Ferrell, and First Lady Michelle Obama are on the docket for Tuesday through Thursday. Meanwhile, the audience will see performances from such varied names as Lady Gaga, Tim McGraw, and Arcade Fire.

Check out The Tonight Show Staring Jimmy Fallon at its brand new time, 12 a.m. ET, on NBC. Click the video below to see a teaser.

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The Tonight Show Starring Jimmy Fallon, Television, Nbc