Supernatural's Crowley will look to Castiel for help in "Soul Survivor."

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The Jensen Ackles-directed episode will see Sam (Jared Padalecki) and Dean (Jensen Ackles) come face-to-face for the first time since Dean's apparent death, but Crowley (Mark Sheppard) will also meet up with an unexpected ally.

Demon Dean is out of control, and his trail of wanton death and destruction will put the King of Hell in a precarious position. Far from his dreams of ruling with the Mark of Cain bearer by his side, Crowley will find his newly recaptured kingdom destabilized by the Deanmon.

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In a bid for help, Crowley will turn to Castiel (Misha Collins) for help. It is unclear what exactly Crowley wants from the dying angel, but there is a chance that Dean has caused so much damage that his demonic buddy wants him cured.

While Dean may "like the disease," Sam and Cas would/will go to the ends of the Earth to cure the former hunter. Sam has the demon cure up his sleeve, but the younger Winchester will probably need Cas on hand to heal the fatal wound that caused Dean's transformation in the first place. PErhapse the duo will have Crowley's backing as well.

Find out more when Supernatural returns to The CW on Oct. 7 at 9 p.m. ET. "Soul Survivor" will air on Oct. 21. Click the video below to see a clip from season 10's third episode.

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Supernatural, Television, The cw