Supernatural's Dean has lost his black eyes, but the former demon still has that pesky Mark of Cain on his arm.

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Let's hope Crowley dropped the First Blade into Marianas Trench, or else the Team Free Will could be sucked back into another round with Dean the homicidal maniac.

If the elder Winchester doesn't come in contact with his kryptonite, will Sam and Dean be able to hit the road with Baby, just taking on one monster at a time? For now, the answer appears to be a resounding yes.

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"Dean still has the mark of Cain. They've got to deal with that. That's got an ugly head that's going to rear itself at one point, they just don't know when," Ackles explained to IGN. "So the fact that they're kind of like snakes in the grass, they're aware of, but right now it's kind of back to business as usual, which is refreshing. We haven't been there in a while."

Business as usual will lead the brothers to check out a werewolf case during "Paper Moon," and Sam and Dean will get an unwelcome blast from their past.

Find out more when Supernatural airs Tuesdays at 9 p.m. ET. Click the video below to see a preview for the series' next episode.

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